ea0099ep244 | Pituitary and Neuroendocrinology | ECE2024
Vamvoukaki Rodanthi
, Kyriakopoulos Georgios
, Ntali Georgia
, Vassiliadi Dimitra
, Vlachou Panagiota
, Koukoula Chrysoula
, Barkas Konstantinos
, Gkalonakis Ioannis
, Tzanela Marinella
, Andoniadou Cynthia
, Xekouki Paraskevi
Background/Aim: Pituitary neuroendocrine tumors (PitNETs), although usually indolent, may display aggressive behavior. YAP/TAZ signalling has been linked to pituitary development and stem cell regulation, with a preliminary study from our group revealing elevated levels and nuclear localization of YAP/TAZ in non-functioning PitNETs (NF-PitNETs). CTGF, a YAP/TAZ target gene, encodes a secreted factor involved in proliferation and angiogenesis, that has been implicated ...